Can Alzheimer's Disease be inherited?
You are surely wondering whether it would make sense and be useful to take precautions to protect yourself from Alzheimer's, especially if you have a case of Alzheimer's in your family or your father or mother has contracted it. The answer is unequivocal: “Yes, it makes absolute sense to take precautions to protect yourself from Alzheimer's, since the disease can, in large part, be inherited .' The latest scientific studies confirm what was in any case already known: Alzheimer's is spread through genetic material. The inherited genes are the so-called ApoE4 gene and the TOMM40 gene, also called simply the 'Alzheimer's Gene.'
In a study published by the New England Journal of Medicine in July 2009 it says:
"People with the Alzheimer's gene begin to have memory declines tied to aging before they reach 60, even if they have no clinical symptoms of dementia".
The study goes on to say that there is a number of firms which offer tests from which you can find out whether you have inherited the Alzheimer's gene ApoE4, including: Island's Decode Genetics' DecodeME and the 23andME Test.
Where the ApoE4 gene is present, it continues, the danger of contracting Alzheimer's increases by 50%. However, it does not necessarily follow that you will contract Alzheimer's, though there is a very high likelihood.
A second gene, the TOMM40 gene, is also said to significantly increase the risk of contracting Alzheimer's, as can be heard from the University of North Carolina, USA. Dr. Allen Roses at Duke University points out that both the ApoE4 and TOMM40 genes are very closely related and that if both are present together the danger that Alzheimer's will be inherited rises to 80-95%.
Doctors usually refrain from having patients tested for the Alzheimer's genes, however, because a positive result causes stress.
However, researchers at the University of Boston have found out that this does not quite correspond to the truth, since according to their study, subjects who received a positive result- i.e. the results showed that they had inherited the Alzheimer's gene- did not show a stressed reaction. Their reaction was no more worried or depressed than people in the placebo group, said Dr. Robert Green in a summary of the study.
Alzheimer's researchers are agreed that prevention is the best method for avoiding the disease- i.e. to take precautions against the disease even before it manifests itself and/or to prevent it.
The maxim that the sooner the disease is recognized, the better the chances of doing something about it also applies to an Alzheimer's diagnosis.
Prof. David Snowdon is certain:
that prevention is the best protection from Alzheimer's, especially and above all if you have a case of Alzheimer's in the family.
He says:
"By the time you have memory problems – it is already too late, which means the disease has already advanced. You possibly should act long time before that happens to try to prevent it from happening.“
Preventative protection against Alzheimer's
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